“Our next goal is to engineer the pluripotent stem cells to make T cells that are suited for treating any individual,” Seet continued. “To do this we need to make sure that the T cells we make are not rejected by a patient’s immune system, and also specifically attack a patient’s tumor cells and not the rest of their body. We can achieve this by engineering these traits in the stem cells, and indeed our goal is to make T cells that not only can be given to any individual, but may function better than T cells from the blood.”
A paper describing the work was recently published in the journal Cell Stem Cell. Other researchers on the work included Gay Crooks and Amélie Montel-Hagen.
Source: Digital Trends